NFKappaB-p65 Polyclonal Antibody

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of RELA, RELA. Four transcript variants encoding different isoforms have been found for RELA.

The Nibrin Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and analysis of Nibrin protein expression in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the Nibrin protein. It has been extensively validated for its specificity and affinity, ensuring reliable and reproducible results.

The Nibrin Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes endogenous levels of Nibrin protein in human, mouse, and rat samples, making it a versatile tool for researchers working in diverse fields.

With its high sensitivity, this antibody allows for the detection of low-abundance Nibrin protein, enabling researchers to study its expression patterns and cellular localization with great precision. Its polyclonal nature ensures a broad epitope recognition, enhancing the chances of successful detection across different experimental conditions.

Furthermore, the Nibrin Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering. The antibody is also accompanied by comprehensive technical support, including detailed protocols and troubleshooting advice, ensuring a seamless and successful experimental workflow.

In summary, the Nibrin Polyclonal Antibody is a reliable and efficient tool for the detection and analysis of Nibrin protein expression. Its high specificity, sensitivity, and versatility make it an invaluable asset for researchers aiming to unravel the biological functions and mechanisms involving Nibrin protein.