NFKappaB-p65 Polyclonal Antibody

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of RELA, RELA. Four transcript variants encoding different isoforms have been found for RELA.

The NFKappaB-p65 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of NFKappaB-p65 protein in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target protein.

The NFKappaB-p65 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to accurately quantify and visualize the expression and localization of NFKappaB-p65 in different tissues and cell types.

With its superior sensitivity and low background, this antibody provides reliable and reproducible results, making it an ideal choice for both basic research and clinical investigations. Its versatility allows for the exploration of NFKappaB-p65's involvement in various cellular processes, such as inflammation, immune response, and cell survival.

Furthermore, the NFKappaB-p65 Polyclonal Antibody has been rigorously validated to ensure its performance and consistency. It is manufactured under strict quality control standards, guaranteeing batch-to-batch reproducibility and reliability.

In summary, the NFKappaB-p65 Polyclonal Antibody is a valuable tool for researchers seeking to investigate the role of NFKappaB-p65 in cellular signaling pathways. Its exceptional sensitivity, specificity, and versatility make it an indispensable asset in the field of molecular biology and biomedical research.