NFKappaB-p65 (Acetyl Lys314/Lys315) Polyclonal Antibody

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for RELA.

The NFKappaB-p65 (Acetyl Lys314/Lys315) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of NFKappaB-p65 protein. This antibody is produced using advanced techniques and is rigorously tested to ensure its quality and reliability.

The NFKappaB-p65 protein plays a crucial role in the regulation of various cellular processes, including inflammation, immune response, and cell survival. The acetylation of lysine residues at positions 314 and 315 has been shown to modulate the activity of NFKappaB-p65, making it an important target for research in the field of immunology and related disciplines.

This polyclonal antibody is raised in rabbits and purified using affinity chromatography to ensure high specificity and minimal cross-reactivity. It has been validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

With its exceptional sensitivity and specificity, the NFKappaB-p65 (Acetyl Lys314/Lys315) Polyclonal Antibody is an invaluable tool for researchers studying the role of NFKappaB-p65 in cellular processes and its potential as a therapeutic target. Its reliable performance and consistent results make it an ideal choice for both basic research and clinical applications.

Order your NFKappaB-p65 (Acetyl Lys314/Lys315) Polyclonal Antibody today and unlock new insights into the intricate mechanisms of cellular regulation and immune response.