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SKU:BT-AP05969

NF-YA Polyclonal Antibody

NF-YA Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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The protein encoded by NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in NFYA product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

The NF-YA Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of NF-YA protein in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional sensitivity and specificity.

NF-YA, also known as Nuclear Factor Y subunit alpha, is a crucial transcription factor that plays a pivotal role in regulating gene expression. It is involved in a wide range of biological processes, including cell proliferation, differentiation, and development. The NF-YA Polyclonal Antibody recognizes and binds to NF-YA protein, enabling researchers to investigate its function and activity in different cellular contexts.

This antibody exhibits outstanding performance in various applications, such as Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated and proven to deliver consistent and reproducible results. The NF-YA Polyclonal Antibody demonstrates minimal cross-reactivity with other proteins, ensuring accurate and specific detection of NF-YA.

With its high affinity and sensitivity, this antibody enables researchers to explore the intricate mechanisms underlying NF-YA-mediated gene regulation. It provides a valuable tool for studying the involvement of NF-YA in various physiological and pathological processes, including cancer, immune response, and neurodevelopment.

The NF-YA Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and saving valuable time in the laboratory. It is produced using high-quality materials and undergoes rigorous quality control to ensure optimal performance and reliability.

In summary, the NF-YA Polyclonal Antibody is an indispensable tool for researchers seeking to unravel the complexities of NF-YA protein function. Its exceptional specificity, sensitivity, and reliability make it an ideal choice for a wide range of applications in molecular biology, cell biology, and biomedical research.

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