Nephrocystin-4 Polyclonal Antibody

NPHP4 encodes a protein involved in renal tubular development and function. Nephrocystin-4 interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants.

The Nephrocystin-4 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Nephrocystin-4 protein in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure its exceptional quality and performance.

Nephrocystin-4, also known as NPHP4, is a crucial protein involved in the regulation of ciliary function and maintenance of renal tubular integrity. Mutations in the NPHP4 gene have been associated with a range of renal disorders, including nephronophthisis, a hereditary cystic kidney disease. Therefore, the accurate detection and quantification of Nephrocystin-4 protein is of utmost importance in understanding the pathogenesis of these disorders.

The Nephrocystin-4 Polyclonal Antibody exhibits high affinity and specificity towards Nephrocystin-4 protein, enabling reliable and precise detection in various experimental applications, such as Western blotting, immunohistochemistry, and immunofluorescence. This antibody has been extensively validated to ensure its consistent performance across different sample types and experimental conditions.

With its exceptional sensitivity, this antibody allows for the detection of even low levels of Nephrocystin-4 protein, facilitating the study of its expression patterns and localization in different tissues and cell types. Its polyclonal nature further enhances its versatility, enabling the detection of multiple epitopes on the target protein.

The Nephrocystin-4 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, ensuring ease of use and compatibility with various laboratory protocols.

In summary, the Nephrocystin-4 Polyclonal Antibody is a reliable and efficient tool for the detection and analysis of Nephrocystin-4 protein. Its exceptional sensitivity, specificity, and versatility make it an invaluable asset for researchers and clinicians studying renal disorders and related pathologies.