NDUFS6 Polyclonal Antibody

NDUFS6 encodes a subunit of the NADH: ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by NDUFS6 is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.

The NDUFS6 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of NDUFS6 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the N-terminal region of human NDUFS6 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The NDUFS6 Polyclonal Antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically recognize NDUFS6 protein in human, mouse, and rat tissues, with minimal cross-reactivity to other proteins. The antibody has also been shown to be highly sensitive, with a detection limit of 0.1 ng of NDUFS6 protein.

This antibody is an essential tool for researchers studying mitochondrial function and oxidative phosphorylation. NDUFS6 is a subunit of complex I of the mitochondrial respiratory chain, and mutations in this gene have been associated with various mitochondrial disorders. The NDUFS6 Polyclonal Antibody can be used to study the expression and localization of NDUFS6 protein in various tissues and cell types, as well as to investigate the role of NDUFS6 in mitochondrial function and disease.

In summary, the NDUFS6 Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for the detection of NDUFS6 protein in various biological samples. It is an essential tool for researchers studying mitochondrial function and oxidative phosphorylation, and it has been extensively validated for use in various applications.