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SKU:BT-AP05848

NDUFA8 Polyclonal Antibody

NDUFA8 Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 encoded by NDUFA8 belongs to the complex I 19 kDa subunit family. Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays an important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

The NDUFA8 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of NDUFA8 protein expression in various biological samples. This antibody is produced using advanced immunization techniques and exhibits excellent affinity and selectivity towards NDUFA8.

NDUFA8, also known as NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8, is a crucial component of the mitochondrial respiratory chain complex I. It plays a vital role in the electron transfer process, which is essential for ATP synthesis and cellular respiration. Dysregulation or dysfunction of NDUFA8 has been implicated in various pathological conditions, including neurodegenerative disorders and metabolic diseases.

The NDUFA8 Polyclonal Antibody is rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, ready for immediate use in various applications. It is compatible with multiple species, including human, mouse, and rat, making it a versatile tool for researchers working in diverse fields of study.

With its exceptional performance and reliability, the NDUFA8 Polyclonal Antibody is an indispensable tool for investigating the role of NDUFA8 in mitochondrial function and its implications in various diseases.

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