ND1 Polyclonal Antibody

MT-ND1 is a Protein Coding gene. Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Diseases associated with MT-ND1 include melas syndrome and leber hereditary optic neuropathy. Among its related pathways are Metabolism and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Gene Ontology (GO) annotations related to this gene include NADH dehydrogenase (ubiquinone) activity.

The ND1 Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the N-terminal region of the ND1 protein. The ND1 Polyclonal Antibody has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence assays.

The ND1 protein is a subunit of the mitochondrial complex I, which is involved in the electron transport chain and oxidative phosphorylation. Dysfunctions in complex I have been implicated in various human diseases, including neurodegenerative disorders and metabolic disorders. The ND1 Polyclonal Antibody can be used to study the expression and localization of the ND1 protein in various tissues and cell types, as well as to investigate the role of complex I in disease pathogenesis.

The ND1 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using a peptide column. This antibody has been tested and validated for use in various species, including human, mouse, rat, and bovine. The ND1 Polyclonal Antibody is a valuable tool for researchers studying mitochondrial function and dysfunction, as well as those investigating the role of complex I in disease pathogenesis.