NCX1 Polyclonal Antibody

In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.

The NCX1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of NCX1 protein expression in various biological samples. This antibody is produced using a polyclonal approach, ensuring a diverse range of epitope recognition and enhanced sensitivity.

The NCX1 Polyclonal Antibody has been rigorously validated for its specificity and reliability in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and precise results.

With its high affinity and specificity, this antibody enables researchers to investigate the role of NCX1 in various physiological and pathological processes. It provides a valuable tool for studying the function and regulation of NCX1 in cardiovascular diseases, neurological disorders, and cancer research.

The NCX1 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and complex antibody preparation. It is available in various sizes to accommodate different experimental requirements.

In summary, the NCX1 Polyclonal Antibody is a reliable and versatile tool for researchers seeking to explore the expression and function of NCX1 protein. Its high specificity, sensitivity, and ease of use make it an essential component in various research applications.