NCAM-L1 Polyclonal Antibody

The protein encoded by L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of L1CAM results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.

The NCAM-L1 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of neural cell adhesion molecule L1 (NCAM-L1) in various biological samples. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity, making it an ideal choice for researchers in the field of neuroscience.

The NCAM-L1 Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It has been rigorously tested for its ability to recognize NCAM-L1 in a variety of species, including human, mouse, and rat. This broad reactivity allows for versatile applications in different experimental models.

This antibody is designed for use in various immunoassays, including Western blotting, immunohistochemistry, and immunofluorescence. It has been optimized for optimal performance in these techniques, providing clear and reliable results. The NCAM-L1 Polyclonal Antibody exhibits minimal cross-reactivity with other related proteins, ensuring accurate and specific detection of NCAM-L1.

With its high affinity and specificity, the NCAM-L1 Polyclonal Antibody offers researchers a valuable tool for studying the role of NCAM-L1 in neural development, plasticity, and regeneration. Its reliable performance and consistent results make it an essential component in any neuroscience laboratory.

In summary, the NCAM-L1 Polyclonal Antibody is a top-quality research reagent that enables precise and accurate detection of NCAM-L1 in various biological samples. Its exceptional sensitivity, specificity, and versatility make it an indispensable tool for researchers investigating the intricate mechanisms of neural cell adhesion molecule L1