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SKU:BT-AP05709

MYLK Polyclonal Antibody

MYLK Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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MYLK, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. MYLK encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.

The MYLK Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of myosin light chain kinase (MYLK) protein in various biological samples. This antibody is produced using state-of-the-art technology and has been rigorously validated to ensure optimal performance and reliability.

The MYLK Polyclonal Antibody exhibits exceptional affinity and specificity towards MYLK protein, making it an ideal choice for a wide range of applications, including western blotting, immunohistochemistry, and immunofluorescence. It recognizes both the phosphorylated and non-phosphorylated forms of MYLK, allowing for comprehensive analysis of MYLK protein expression and activation status.

With its superior sensitivity, the MYLK Polyclonal Antibody enables accurate and precise quantification of MYLK protein levels even in low abundance samples. Its robust performance ensures consistent and reproducible results, making it an indispensable tool for researchers and scientists working in the fields of cell biology, molecular biology, and biochemistry.

The MYLK Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, allowing for easy storage and handling. Each batch of the antibody undergoes stringent quality control measures to guarantee batch-to-batch consistency and reliability.

Choose the MYLK Polyclonal Antibody for its exceptional performance, reliability, and versatility. Experience accurate and precise detection and quantification of MYLK protein with this high-quality antibody, enabling groundbreaking discoveries and advancements in the field of biomedical research.

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