MSH3 Polyclonal Antibody

DNA mismatch repair protein Msh3 encoded by MSH3 forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.

The mtTFA Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of mitochondrial transcription factor A (mtTFA) in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity for mtTFA detection.

The mtTFA Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to investigate the expression and localization of mtTFA in different tissues and cell types, facilitating a comprehensive understanding of its role in mitochondrial biogenesis and function.

With its superior specificity, the mtTFA Polyclonal Antibody minimizes the risk of cross-reactivity with other proteins, ensuring accurate and reliable results. It offers excellent signal-to-noise ratios, allowing for precise quantification and analysis of mtTFA expression levels.

This antibody is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming preparation. It is compatible with various detection systems and can be used in combination with other antibodies for multiplex experiments.

The mtTFA Polyclonal Antibody is manufactured under strict quality control standards, guaranteeing consistent performance and reproducibility. It is validated for use in diverse species, including human, mouse, and rat, making it a versatile tool for researchers in various fields of study.

In summary, the mtTFA Polyclonal Antibody is a highly reliable and specific reagent that enables accurate detection and analysis of mtTFA in various biological samples. Its exceptional performance, convenience, and compatibility make it an invaluable tool for researchers investigating mitochondrial biogenesis and function.