Skip to product information
1 of 1

BT Lab

SKU:BT-AP05600

MRP-S12 Polyclonal Antibody

MRP-S12 Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
Host
Ab type

28S ribosomal protein S12 mitochondrial (mitochondrial ribosomal protein S12) is encoded by nuclear genes MRPS12 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene; all three variants encode the same protein.

The MRP-S2 Polyclonal Antibody is a highly specific and reliable tool for the detection and quantification of MRP-S2 protein in various biological samples. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity, ensuring accurate and reproducible results.

The MRP-S2 Polyclonal Antibody is produced using state-of-the-art techniques, guaranteeing high purity and batch-to-batch consistency. It has been rigorously tested for cross-reactivity with other proteins to ensure its specificity for MRP-S2. This antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

With its superior performance characteristics, the MRP-S2 Polyclonal Antibody is an invaluable tool for researchers and scientists studying the role of MRP-S2 in various biological processes. Its high affinity and sensitivity enable the detection of low abundance MRP-S2 protein, facilitating accurate quantification and analysis.

The MRP-S2 Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided in a liquid form, eliminating the need for reconstitution, and is stable for long-term storage at -20°C. Each vial contains a sufficient amount of antibody for multiple experiments, ensuring cost-effectiveness and minimizing wastage.

In summary, the MRP-S2 Polyclonal Antibody is a reliable and specific tool for the detection and quantification of MRP-S2 protein. Its exceptional performance characteristics, user-friendly format, and suitability for various applications make it an ideal choice for researchers and scientists in the field.

View full details