MRP-L47 Polyclonal Antibody

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL47 (mitochondrial ribosomal protein L47) encodes a 39S subunit protein. MRPL47 is immediately adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identified.

The MRP-L47 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of MRP-L47 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the MRP-L47 protein.

The MRP-L47 Polyclonal Antibody exhibits exceptional affinity and selectivity towards its target protein, ensuring accurate and reliable results in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its high sensitivity allows for the detection of even low levels of MRP-L47 protein, making it an invaluable tool for researchers studying its expression and function.

This antibody is supplied as a liquid formulation, ready for immediate use. It has been rigorously tested for quality and performance, ensuring consistent and reproducible results. The MRP-L47 Polyclonal Antibody is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering.

With its exceptional specificity, sensitivity, and reliability, the MRP-L47 Polyclonal Antibody is an essential tool for researchers and scientists in the field of molecular biology and immunology. Its application in various techniques enables the elucidation of MRP-L47 protein's role in cellular processes and disease mechanisms, contributing to advancements in biomedical research.