MRE11 Polyclonal Antibody

MRE11A encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. MRE11A has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

The MRE11 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of MRE11 protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring its high quality and reliability for research applications.

The MRE11 protein plays a crucial role in DNA repair and maintenance of genomic stability. It is involved in the recognition and processing of DNA double-strand breaks, making it an essential component of the cellular response to DNA damage. The MRE11 Polyclonal Antibody enables researchers to investigate the function and regulation of MRE11 in diverse cellular processes.

This antibody exhibits exceptional sensitivity and specificity, allowing for accurate and precise detection of MRE11 protein expression levels. It has been extensively validated in various experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence. The MRE11 Polyclonal Antibody consistently delivers reliable and reproducible results, making it an indispensable tool for molecular and cellular biology research.

Furthermore, the MRE11 Polyclonal Antibody is manufactured using state-of-the-art techniques and undergoes stringent quality control measures. It is produced in a host species that ensures minimal cross-reactivity, thereby reducing the risk of non-specific binding. This antibody is also provided in a convenient format, allowing for easy handling and storage.

In summary, the MRE11 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of MRE11 protein expression. Its exceptional sensitivity, specificity, and quality make it an invaluable asset for researchers studying DNA repair, genomic stability, and related cellular processes.