MMP-9 Polyclonal Antibody

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

The MMP-9 Polyclonal Antibody is a highly specific and sensitive antibody that is designed to detect and quantify the expression of matrix metalloproteinase-9 (MMP-9) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human MMP-9 protein. The resulting polyclonal antibody is purified using protein A affinity chromatography and is validated for its specificity and sensitivity using various techniques such as Western blotting, immunohistochemistry, and ELISA.

The MMP-9 Polyclonal Antibody is a valuable tool for researchers studying the role of MMP-9 in various physiological and pathological processes such as tissue remodeling, wound healing, cancer metastasis, and inflammation. This antibody can be used to detect MMP-9 expression in various sample types including cell lysates, tissue homogenates, and biological fluids such as serum and plasma. The antibody is suitable for use in various applications such as Western blotting, immunohistochemistry, and ELISA.

The MMP-9 Polyclonal Antibody is supplied as a liquid in phosphate-buffered saline (PBS) containing 0.02% sodium azide as a preservative. The antibody is available in various sizes and formats to meet the specific needs of researchers. The antibody is stable for long-term storage at -20°C and can be used for multiple experiments without loss of activity.

In summary, the MMP-9 Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for researchers studying the role of MMP-9 in various physiological and pathological processes. The antibody is validated for its specificity and sensitivity and is available in various sizes and formats to meet the specific needs of researchers.