MMP-15 Polyclonal Antibody

MMP15 encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression.

The MMP-15 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of matrix metalloproteinase-15 (MMP-15) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human MMP-15. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in various applications, including Western blotting, immunohistochemistry, and ELISA.

The MMP-15 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting MMP-15 in various biological samples, including human tissues and cell lines. This antibody has been shown to recognize both the pro-form and active form of MMP-15, making it a valuable tool for studying the regulation and function of this important protease.

In addition to its high specificity and sensitivity, the MMP-15 Polyclonal Antibody is also highly reproducible and reliable, ensuring consistent results across multiple experiments. This antibody is supplied in a convenient format, with a concentration of 1 mg/mL, and can be easily diluted to the desired working concentration.

Overall, the MMP-15 Polyclonal Antibody is a valuable tool for researchers studying the role of MMP-15 in various biological processes, including cancer progression, tissue remodeling, and inflammation. Its high specificity, sensitivity, and reproducibility make it an ideal choice for a wide range of applications in both basic and clinical research.