MMP-11 Polyclonal Antibody

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, Stromelysin-3 encoded by MMP11 is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.

The MMP-11 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of matrix metalloproteinase-11 (MMP-11) in various biological samples. This antibody is produced using state-of-the-art techniques, ensuring high purity and quality.

Matrix metalloproteinases (MMPs) are a family of enzymes that play a crucial role in tissue remodeling and degradation of extracellular matrix components. MMP-11, also known as stromelysin-3, is a member of the MMP family and is involved in various physiological and pathological processes, including tissue development, wound healing, and cancer progression.

The MMP-11 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various experimental settings. It exhibits minimal cross-reactivity with other MMP family members, ensuring accurate and reliable results. This antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assays (ELISA).

With its high affinity and specificity, the MMP-11 Polyclonal Antibody offers researchers a valuable tool for studying the role of MMP-11 in various biological processes. Its reliable performance and consistent results make it an ideal choice for both basic research and clinical applications.

Order the MMP-11 Polyclonal Antibody today and unlock new insights into the function and regulation of MMP-11 in health and disease.