MKP-5 Polyclonal Antibody

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants.

The MKP-5 Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of MKP-5 protein levels in various biological samples. This antibody has been rigorously validated for its specificity and performance, ensuring reliable and reproducible results.

MKP-5, also known as dual specificity phosphatase 10 (DUSP10), is a member of the mitogen-activated protein kinase phosphatase (MKP) family. It plays a crucial role in the regulation of cellular signaling pathways by dephosphorylating and inactivating mitogen-activated protein kinases (MAPKs). MKP-5 has been implicated in various physiological and pathological processes, including cell proliferation, differentiation, and immune response.

The MKP-5 Polyclonal Antibody has been developed using high-quality immunogens and advanced immunization techniques. It exhibits high affinity and specificity towards MKP-5, enabling accurate detection and quantification of this protein in complex biological samples. This antibody has been extensively tested and validated in various experimental conditions, including Western blotting, immunohistochemistry, and immunofluorescence.

Key features of the MKP-5 Polyclonal Antibody include its excellent sensitivity, low background noise, and minimal cross-reactivity with other proteins. It offers a reliable and robust tool for researchers studying the role of MKP-5 in cellular signaling pathways and its implications in various diseases, such as cancer, inflammation, and neurodegenerative disorders.

The MKP-5 Polyclonal Antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is provided in a ready-to-use format, eliminating the need for time-consuming antibody preparation steps. This antibody is suitable for use in both basic research and clinical applications, making it a versatile tool for scientists and clinicians alike.

In summary, the MKP-5 Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of MKP-5 protein levels. Its excellent performance, reliability, and versatility make it an essential reagent for researchers investigating the role of MKP-5 in cellular signaling pathways and its potential as a therapeutic target in various diseases.