MKP-4 Polyclonal Antibody

The dual specificity phosphatase 9 encoded by DUSP9 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants.

The MKP-4 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of MKP-4 protein in various biological samples. This antibody has been meticulously developed and rigorously validated to ensure optimal performance and reliability.

The MKP-4 Polyclonal Antibody exhibits exceptional affinity and selectivity towards the MKP-4 protein, enabling accurate and precise measurement of its expression levels. It is produced using state-of-the-art techniques, resulting in a high-quality antibody with minimal batch-to-batch variation.

This antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively tested and validated in various experimental conditions, ensuring consistent and reproducible results.

The MKP-4 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy handling and storage. The antibody is stable and long-lasting, ensuring reliable performance over an extended period.

With its exceptional specificity, sensitivity, and reliability, the MKP-4 Polyclonal Antibody is an indispensable tool for researchers and scientists studying the MKP-4 protein and its role in various biological processes. It offers a valuable resource for understanding the molecular mechanisms underlying disease pathogenesis and for developing potential therapeutic interventions.

Order the MKP-4 Polyclonal Antibody today and unlock new insights into the intricate workings of the MKP-4 protein, advancing scientific knowledge and paving the way for innovative discoveries in the field of biomedical research.