MKP-2 Polyclonal Antibody

The dual specificity phosphatase 4 encoded by DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.

The MKP-2 Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of MKP-2 protein in various biological samples. This antibody has been rigorously tested and validated to ensure its reliability and accuracy in experimental settings.

The MKP-2 Polyclonal Antibody is produced using state-of-the-art techniques, resulting in a high affinity and specificity towards the target protein. It has been extensively characterized to ensure minimal cross-reactivity with other proteins, ensuring the utmost specificity in detecting MKP-2.

This antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been optimized for use in both human and animal samples, making it a versatile tool for researchers in various fields.

The MKP-2 Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and complicated preparation steps.

With its exceptional sensitivity and specificity, the MKP-2 Polyclonal Antibody is an invaluable tool for researchers studying the role of MKP-2 in various biological processes. Its reliable performance and ease of use make it an essential component in any laboratory setting.