Midline-1 Polyclonal Antibody

Midline-1 encoded by this MID1 is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. Midline-1 is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing; however, the full-length nature of some of the variants has not been determined.

The Midline-1 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Midline-1 protein expression in various biological samples. This antibody has been meticulously developed and validated to ensure exceptional performance and accuracy in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Midline-1 Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling the precise identification and quantification of Midline-1 protein levels in both normal and diseased tissues. Its high affinity for Midline-1 protein ensures minimal background noise and reliable results, even in complex biological matrices.

This antibody has been rigorously tested and validated to ensure consistent and reproducible results. Its exceptional performance characteristics, including high signal-to-noise ratio and low cross-reactivity, make it an ideal choice for researchers and scientists working in the field of Midline-1 protein research.

The Midline-1 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. Its long shelf life and stability ensure reliable and consistent results over an extended period of time.

In summary, the Midline-1 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Midline-1 protein expression. With its exceptional performance characteristics and ease of use, this antibody is an invaluable asset for researchers and scientists in their quest to unravel the complexities of Midline-1 protein function and its role in various biological processes.