MIA Polyclonal Antibody

Tumorigenesis is a process that is mediated by a network of membrane, cytosolic and nuclear associated factors, which regulate proliferation and cell-matrix interaction through signaling cascades. The phenotype of malignant melanomas in vivo depends on the global expression of stimulatory or inhibitory factors generated in both the tumors cells and their environment. One example, Melanoma inhibitory activity (cartilage-derived retinoic acid-sensitive protein (CD-RAP), MIA) is a Src homology 3 (SH3)-like domain containing protein that is secreted from chondrocytes and malignant melanoma cells. MIA is translated as a 131-amino acid pro-form and processed into a mature 107-amino acid protein after cleavage of a secretion signal. MIA is expressed during chondrogenesis and in mature chondrocytes, suggesting that MIA is necessary for normal cartilage cell phenotype. MIA mRNA is present in carcinomas of the colon, ovary, kidney, and head/neck, and may represent a marker to monitor melanomic activity.

The MIA Polyclonal Antibody is a highly specific and reliable tool for the detection and quantification of Melanoma Inhibitory Activity (MIA) protein in various biological samples. This antibody has been meticulously developed and rigorously validated to ensure optimal performance and accuracy in research and diagnostic applications.

The MIA Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling precise and reproducible results. It has been extensively tested in a variety of experimental conditions, including Western blotting, immunohistochemistry, and ELISA, demonstrating consistent and robust performance across multiple platforms.

This antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It is derived from a polyclonal source, resulting in a diverse population of antibodies that recognize different epitopes of the MIA protein. This broad recognition profile enhances the versatility and reliability of the antibody, making it suitable for a wide range of experimental designs and applications.

The MIA Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided as a liquid formulation, eliminating the need for reconstitution and minimizing the risk of sample contamination. The antibody is also available in various sizes to accommodate different experimental requirements.

With its exceptional performance, reliability, and ease of use, the MIA Polyclonal Antibody is an indispensable tool for researchers and clinicians studying the role of MIA protein in various biological processes and diseases, particularly in the context of melanoma. Trust in the MIA Polyclonal Antibody to deliver accurate and reproducible results, enabling advancements in scientific understanding and clinical diagnostics.