Melanopsin Polyclonal Antibody

Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. OPN4 encodes a photoreceptive opsin protein melanopsin that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. Melanopsin functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms.

The Melanopsin Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of melanopsin protein in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.

Melanopsin, a photopigment found in the retina, plays a crucial role in regulating various physiological processes, including circadian rhythm and pupillary light reflex. The Melanopsin Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting melanopsin in both human and animal tissues.

This antibody exhibits exceptional performance in various applications, including immunohistochemistry, immunofluorescence, and Western blotting. It demonstrates a strong signal-to-noise ratio, allowing for accurate and reliable quantification of melanopsin expression levels.

The Melanopsin Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, ensuring ease of use and compatibility with a wide range of experimental protocols.

With its exceptional specificity, sensitivity, and ease of use, the Melanopsin Polyclonal Antibody is an indispensable tool for researchers studying the role of melanopsin in various physiological processes. Trust in its superior performance to advance your research and gain valuable insights into the intricate mechanisms of the visual system.