MBD3 Polyclonal Antibody

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. MBD3 belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). Methyl-CpG-binding domain protein 3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene.

The MBD3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of MBD3 protein in various biological samples. This antibody has been rigorously validated and exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The MBD3 Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It has been affinity-purified from rabbit serum, resulting in a highly specific antibody that recognizes the MBD3 protein with minimal cross-reactivity to other proteins.

With its exceptional sensitivity, this antibody allows for the detection of even low levels of MBD3 protein, making it an ideal choice for researchers working with limited sample quantities. Its high specificity ensures accurate and reliable results, minimizing the risk of false positives or false negatives.

The MBD3 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering. The antibody is stable and can be stored at -20°C, ensuring long-term usability.

In summary, the MBD3 Polyclonal Antibody is a reliable and versatile tool for the detection and quantification of MBD3 protein. Its high specificity, sensitivity, and stability make it an essential component for any researcher studying MBD3-related processes and pathways.