MB67 Polyclonal Antibody

NR1I3 (nuclear receptor subfamily 1 group I member 3) encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for NR1I3.

The MB67 Polyclonal Antibody is a highly specific and reliable tool for various research applications. This antibody is produced using state-of-the-art techniques, ensuring exceptional quality and performance. It has been extensively validated for its specificity and sensitivity, making it an ideal choice for immunohistochemistry, immunofluorescence, and Western blotting experiments.

The MB67 Polyclonal Antibody exhibits a strong affinity towards its target antigen, enabling accurate and precise detection. It has been rigorously tested against a wide range of samples, including human, mouse, and rat tissues, ensuring its versatility and applicability across different species.

This antibody offers exceptional signal-to-noise ratio, minimizing background noise and providing clear and reliable results. Its high sensitivity allows for the detection of low-abundance targets, making it suitable for even the most challenging experiments.

The MB67 Polyclonal Antibody is supplied in a convenient and user-friendly format, ensuring ease of use and storage. It is provided in a liquid form, eliminating the need for reconstitution, and is stable for long-term storage at -20°C. Each vial contains a sufficient amount of antibody for multiple experiments, ensuring cost-effectiveness and minimizing wastage.

In summary, the MB67 Polyclonal Antibody is a superior research tool that offers exceptional specificity, sensitivity, and reliability. Its versatility and ease of use make it an essential component for any laboratory conducting immunohistochemistry, immunofluorescence, or Western blotting experiments. Trust in the MB67 Polyclonal Antibody for accurate and reproducible results in your research endeavors.