MASTL Polyclonal Antibody

MASTL (microtubule associated serine/threonine kinase like) encodes a microtubule-associated serine/threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus.

The MASTL Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminus of the human MASTL protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in Western blotting, immunohistochemistry, and immunofluorescence assays.

The MASTL Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting MASTL protein expression in various cell lines and tissues. This antibody recognizes a single band of approximately 60 kDa in Western blotting and shows strong staining in the cytoplasm of cells in immunohistochemistry and immunofluorescence assays.

This antibody is an essential tool for researchers studying the role of MASTL in cell cycle regulation, mitosis, and cancer. It can be used to investigate the expression and localization of MASTL in various cell types and tissues, as well as to study the effects of MASTL inhibition or overexpression on cell proliferation and survival.

In summary, the MASTL Polyclonal Antibody is a reliable and high-quality reagent that can be used in a wide range of research applications. Its specificity and sensitivity make it an ideal tool for investigating the function of MASTL in various biological processes.