MARK1/2/3/4 Polyclonal Antibody

MARK1 is a Protein Coding gene. Serine/threonine-protein kinase MARK1 involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3). Diseases associated with MARK1 include tauopathy and alzheimer disease. Among its related pathways are Regulation of Microtubule Cytoskeleton. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is LOC102724428.

The Mas1-like Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Mas1-like receptors in various biological samples. This antibody is produced through a rigorous process of immunization and purification, ensuring its high affinity and specificity towards the target antigen.

The Mas1-like Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its superior sensitivity allows for the detection of even low abundance Mas1-like receptors, enabling researchers to obtain accurate and reliable results.

This antibody is manufactured using state-of-the-art techniques and undergoes stringent quality control measures to ensure batch-to-batch consistency and reproducibility. Its high purity and low background staining contribute to the generation of clear and precise data, facilitating the interpretation and analysis of experimental results.

The Mas1-like Polyclonal Antibody is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming and complex preparation steps. Its long shelf life and stability make it an ideal choice for long-term storage and repeated use, providing researchers with a cost-effective solution for their experimental needs.

In summary, the Mas1-like Polyclonal Antibody is a reliable and efficient tool for the detection and analysis of Mas1-like receptors. Its high specificity, sensitivity, and ease of use make it an invaluable asset for researchers in the fields of molecular biology, pharmacology, and neuroscience.