LRRK1 Polyclonal Antibody

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. LRRK1 (leucine-rich repeat serine/threonine-protein kinase 1), also known as RIPK6, Roco1 or KIAA1790, is a 2038 amino acid cytoplasmic protein that contains one protein kinase domain, four ANK repeats and 11 leucine-rich repeats and belongs to the Ser/Thr protein kinase family. Using magnesium as a cofactor, LRRK1 catalyzes the ATP-dependent phosphorylation of target proteins. The gene encoding LRRK1, which is expressed as four alternatively spliced isoforms, is thought to be involved in the pathogenesis of Parkinson's disease.

The LRRK1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of LRRK1 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards LRRK1.

The LRRK1 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to accurately quantify and visualize LRRK1 protein levels in tissues, cells, and other biological specimens.

With its superior sensitivity and specificity, this antibody allows for precise and reliable results, facilitating in-depth investigations into the role of LRRK1 in various physiological and pathological processes. Its robust performance ensures reproducibility and consistency, making it an indispensable tool for researchers in the field of molecular biology and biomedical research.

The LRRK1 Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and saving valuable time in the laboratory. It is manufactured under strict quality control standards, guaranteeing batch-to-batch consistency and reliability.

Choose the LRRK1 Polyclonal Antibody for your research needs and unlock new insights into the function and regulation of LRRK1 protein.