LRP1 Polyclonal Antibody

LRP1 encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients.

The LRP1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) in various biological samples. This antibody is produced using state-of-the-art techniques, ensuring high affinity and specificity towards LRP1.

LRP1 is a multifunctional cell surface receptor that plays a crucial role in various physiological processes, including lipid metabolism, endocytosis, and signal transduction. Dysregulation of LRP1 has been implicated in numerous diseases, such as Alzheimer's disease, atherosclerosis, and cancer. Therefore, accurate measurement of LRP1 expression levels is of great importance in both research and clinical settings.

The LRP1 Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been rigorously validated to ensure reliable and reproducible results. This antibody demonstrates minimal cross-reactivity with other related proteins, ensuring specificity in target detection.

With its high sensitivity and specificity, the LRP1 Polyclonal Antibody is an indispensable tool for researchers and clinicians studying LRP1-related pathways and diseases. Its reliable performance and ease of use make it an ideal choice for a wide range of applications. Trust in the LRP1 Polyclonal Antibody to provide accurate and precise results in your research endeavors.