LRAT Polyclonal Antibody

Lecithin retinol acyltransferase encoded by LRAT localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.

The LRAT Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of lecithin retinol acyltransferase (LRAT) protein in various biological samples. LRAT is a key enzyme involved in the visual cycle, playing a crucial role in the synthesis of 11-cis-retinol, a vital component for the regeneration of visual pigments in the retina. This antibody has been meticulously developed and rigorously validated to ensure exceptional performance and reliability.

The LRAT Polyclonal Antibody exhibits exceptional affinity and specificity towards LRAT protein, enabling accurate and precise detection even at low concentrations. It has been extensively tested in a variety of experimental conditions, including Western blotting, immunohistochemistry, and immunofluorescence, consistently delivering robust and reproducible results. Its broad reactivity across multiple species, including human, mouse, and rat, further enhances its versatility and applicability in diverse research settings.

This antibody is manufactured using state-of-the-art techniques and undergoes stringent quality control measures to guarantee batch-to-batch consistency and optimal performance. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. The LRAT Polyclonal Antibody is provided in a convenient format, ensuring ease of use and facilitating seamless integration into laboratory workflows.

Researchers and scientists in the fields of ophthalmology, visual neuroscience, and retinal biology will greatly benefit from the LRAT Polyclonal Antibody's exceptional sensitivity, specificity, and reliability. Its ability to accurately detect and quantify LRAT protein levels in various biological samples opens up new avenues for investigating the visual cycle and understanding the underlying mechanisms of retinal diseases. Trust in the LRAT Polyclonal Antibody to deliver precise and reproducible results, enabling groundbreaking discoveries and advancements in the field of vision research.