LIGHT Polyclonal Antibody

The protein encoded by TNFSF14 (tumor necrosis factor superfamily member 14) is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

The LIGHT Polyclonal Antibody is a highly specific and sensitive tool for the detection of LIGHT protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human LIGHT protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the target protein, making it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and ELISA.

The LIGHT Polyclonal Antibody is designed to recognize both the soluble and membrane-bound forms of the LIGHT protein, which is a member of the tumor necrosis factor (TNF) superfamily. This protein is involved in a variety of biological processes, including immune regulation, inflammation, and cell survival. The ability to detect LIGHT protein in biological samples is therefore of great importance in both basic research and clinical applications.

The LIGHT Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum using protein A chromatography. The antibody is provided in a liquid format, with a concentration of 1 mg/ml, and is suitable for use in a variety of experimental settings. The antibody has been validated for use in human, mouse, and rat samples, and has been shown to exhibit excellent sensitivity and specificity in these species.

Overall, the LIGHT Polyclonal Antibody is a reliable and effective tool for the detection of LIGHT protein in biological samples. Its high specificity and sensitivity make it an ideal choice for a wide range of applications, and its ease of use and versatility make it a valuable addition to any laboratory's toolkit.