Lambda 5 Polyclonal Antibody

Lambda 5 (also called Immunoglobulin lambda-like polypeptide 1 or CD179b antigen) and VpreB comprise the surrogate light chain of the pre-B cell receptor complex. SL chain is also part of a quality control mechanism that tests a m-chain for its ability to pair with conventional L chains. It can form Ig-like complexes with the heavy (H) chain, the DHJHC m-protein or the p55 chain. Production of the surrogate light chain begins at the stage of pro-B cells, continues during the pre-B-cell stage and halts at the immature B cell stage. Once pre-BCR is expressed, SL chain expression is turned off. As pre-B II cells proliferate, SL is diluted out, thus limiting pre-BCR formation. Lambda 5 is critical for B cell development in mammals. Expression of Lambda 5 is highest in liver, pre- B-lymphocytes and bone marrow, the major source of B cell precursors.

The Lambda 5 Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in a wide range of research applications. This antibody is produced using advanced techniques that ensure high purity and consistency, making it an ideal choice for use in a variety of assays, including Western blotting, ELISA, and immunohistochemistry.

The Lambda 5 Polyclonal Antibody is designed to recognize and bind to the lambda 5 protein, which is a key component of the pre-B cell receptor complex. This protein plays a critical role in the development and maturation of B cells, making it an important target for research in immunology and related fields.

This antibody has been extensively validated for use in a variety of applications, and has been shown to provide reliable and reproducible results. It is available in a range of formats and sizes to suit different experimental needs, and can be used with a variety of detection methods to achieve optimal results.

Overall, the Lambda 5 Polyclonal Antibody is a high-quality research tool that offers exceptional performance and versatility. Whether you are studying B cell development, immunology, or related fields, this antibody is an excellent choice for your research needs.