Lambda 5 Polyclonal Antibody

The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. IGLL1 encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.

The Lambda 5 Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in a wide range of research applications. This antibody is produced using advanced techniques that ensure high purity and consistency, making it an ideal choice for use in a variety of assays, including Western blotting, ELISA, and immunohistochemistry.

The Lambda 5 Polyclonal Antibody is designed to recognize and bind to the lambda 5 protein, which is a key component of the pre-B cell receptor complex. This protein plays a critical role in the development and maturation of B cells, making it an important target for research in immunology and related fields.

This antibody has been extensively validated for use in a variety of applications, and has been shown to provide reliable and reproducible results. It is available in a range of formats and sizes to suit different experimental needs, and can be used with a variety of detection methods to achieve optimal results.

Overall, the Lambda 5 Polyclonal Antibody is a high-quality research tool that offers exceptional performance and versatility. Whether you are studying B cell development, immunology, or related fields, this antibody is an excellent choice for your research needs.