Ku-80 Polyclonal Antibody

X-ray repair cross-complementing protein 5 encoded by XRCC5 is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. XRCC5 functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in XRCC5 is associated with cancer in patients of varying radiosensitivity.

The Ku-80 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Ku-80 protein in various biological samples. This antibody is produced through a rigorous process of immunization and purification, ensuring its high affinity and specificity towards the target protein.

The Ku-80 Polyclonal Antibody exhibits exceptional sensitivity, enabling the detection of even low levels of Ku-80 protein. It is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. With its superior performance, this antibody provides accurate and reproducible results, making it an indispensable tool for researchers and scientists in the field of molecular biology.

This antibody is manufactured using state-of-the-art techniques and undergoes stringent quality control measures to ensure its reliability and consistency. It is supplied in a convenient and ready-to-use format, allowing for easy and efficient experimentation.

The Ku-80 Polyclonal Antibody is an essential component in the study of DNA repair mechanisms and the regulation of genomic stability. Its exceptional specificity and sensitivity make it an invaluable tool for investigating the role of Ku-80 protein in various cellular processes.

Choose the Ku-80 Polyclonal Antibody for its exceptional performance, reliability, and versatility. With its high specificity and sensitivity, this antibody will undoubtedly enhance your research and contribute to the advancement of scientific knowledge in the field of molecular biology.