KOR-1 Polyclonal Antibody

OPRK1 encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in OPRK1 have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

The KOR-1 Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the KOR-1 protein. The resulting polyclonal antibody has been extensively characterized and validated for its specificity and sensitivity in detecting KOR-1 protein expression in various tissues and cell types.

The KOR-1 Polyclonal Antibody is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically detect KOR-1 protein expression in various tissues, including brain, liver, and kidney. This antibody has also been shown to be highly sensitive, with a detection limit of 0.1 ng/mL.

In addition to its high specificity and sensitivity, the KOR-1 Polyclonal Antibody is also highly reproducible, ensuring consistent results across multiple experiments. It is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum, and is available in various sizes to meet the needs of different research applications.

Overall, the KOR-1 Polyclonal Antibody is a reliable and effective tool for studying KOR-1 protein expression in various tissues and cell types. Its high specificity, sensitivity, and reproducibility make it an ideal choice for researchers looking to investigate the role of KOR-1 in various biological processes.