KIR6.2 Polyclonal Antibody

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. ATP-sensitive inward rectifier potassium channel 11 encoded by KCNJ11 is an integral membrane protein and inward-rectifier type potassium channel. ATP-sensitive inward rectifier potassium channel 11, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

The KIR6.2 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of KIR6.2 protein expression in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional sensitivity and specificity.

The KIR6.2 Polyclonal Antibody is produced by immunizing animals with a synthetic peptide corresponding to a specific region of the KIR6.2 protein. This rigorous immunization process guarantees the generation of high-affinity antibodies that specifically recognize the target protein.

This antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent reactivity across a wide range of species, making it a versatile tool for researchers working with different model organisms.

The KIR6.2 Polyclonal Antibody offers numerous advantages over other commercially available antibodies. Its exceptional sensitivity allows for the detection of low-abundance KIR6.2 protein, enabling researchers to obtain accurate and reliable results. Additionally, its high specificity ensures minimal cross-reactivity with other proteins, reducing the risk of false-positive or false-negative results.

Furthermore, this antibody demonstrates excellent reproducibility, providing consistent and reliable results across multiple experiments. Its long shelf life and stability make it a cost-effective choice for long-term studies.

In summary, the KIR6.2 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of KIR6.2 protein expression. Its exceptional sensitivity, specificity, and reproducibility make it an invaluable asset for researchers in the field of molecular biology and related disciplines.