KIR5.1 Polyclonal Antibody

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which tends to allow potassium to flow into rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may function in fluid and pH balance regulation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]KCNJ16 (Potassium Voltage-Gated Channel Subfamily J Member 16) is a Protein Coding gene. Diseases associated with KCNJ16 include sesame syndrome and body dysmorphic disorder. Among its related pathways are Transmission across Chemical Synapses and Inwardly rectifying K+ channels. GO annotations related to this gene include inward rectifier potassium channel activity. An important paralog of this gene is KCNJ3. nward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance. In the kidney, together with KCNJ10, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules (PubMed: 24561201).

The KIR5.1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of KIR5.1 protein expression in various biological samples. This antibody is produced through a rigorous process of immunization and purification, ensuring its high affinity and specificity towards KIR5.1.

With its exceptional performance, the KIR5.1 Polyclonal Antibody offers researchers a reliable and accurate means to investigate the role of KIR5.1 in physiological and pathological processes. It can be utilized in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The KIR5.1 Polyclonal Antibody exhibits minimal cross-reactivity with other related proteins, guaranteeing precise and reliable results. Its superior sensitivity allows for the detection of even low levels of KIR5.1 expression, enabling researchers to explore its potential implications in various diseases and conditions.

This antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and saving valuable time in the laboratory. It is available in different sizes to accommodate various experimental needs.

Choose the KIR5.1 Polyclonal Antibody for its exceptional quality, reliability, and versatility, and unlock new insights into the function and significance of KIR5.1 in biological systems.