KIR2.1 Polyclonal Antibody

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Inward rectifier potassium channel 2 encoded by KCNJ2 is an integral membrane protein and inward-rectifier type potassium channel. Inward rectifier potassium channel 2, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.

The KIR2.1 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection and quantification of KIR2.1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human KIR2.1 protein. The resulting polyclonal antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The KIR2.1 protein is a member of the inward rectifier potassium channel family, which plays a critical role in regulating the electrical activity of cells. Dysregulation of KIR2.1 has been implicated in various diseases, including cardiac arrhythmias, epilepsy, and cancer. Therefore, the KIR2.1 Polyclonal Antibody is an essential tool for researchers studying the function and regulation of KIR2.1 in health and disease.

This antibody is supplied as a purified IgG fraction, which has been affinity-purified using a protein A column. It is provided in a liquid format, ready to use for various applications. The KIR2.1 Polyclonal Antibody is highly specific and sensitive, with minimal cross-reactivity with other proteins. It has been validated for use in various species, including human, mouse, and rat.

In summary, the KIR2.1 Polyclonal Antibody is a highly specific and sensitive antibody that is essential for researchers studying the function and regulation of KIR2.1 protein in various biological samples. Its high specificity and sensitivity make it an ideal tool for various applications, including Western blotting, immunohistochemistry, and immunofluorescence.