KCNQ4 Polyclonal Antibody

Potassium voltage-gated channel subfamily KQT member 4 encoded by KCNQ4 forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.

The KCNQ4 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of KCNQ4 protein expression in various biological samples. This antibody is produced using a polyclonal approach, ensuring a diverse range of epitope recognition and enhanced sensitivity.

The KCNQ4 Polyclonal Antibody exhibits exceptional specificity towards the KCNQ4 protein, a member of the voltage-gated potassium channel family. This antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

With its high affinity and selectivity, the KCNQ4 Polyclonal Antibody enables accurate and reliable detection of KCNQ4 protein expression levels in both normal and pathological conditions. Its robust performance ensures consistent and reproducible results, making it an ideal choice for researchers and scientists working in the field of ion channel research.

Furthermore, the KCNQ4 Polyclonal Antibody is manufactured using state-of-the-art techniques and undergoes rigorous quality control measures to ensure its reliability and consistency. It is supplied in a convenient and ready-to-use format, allowing for easy integration into various experimental protocols.

In summary, the KCNQ4 Polyclonal Antibody is a valuable tool for investigating the role of KCNQ4 protein in cellular processes and disease mechanisms. Its exceptional specificity, sensitivity, and reliability make it an indispensable asset for researchers seeking to unravel the complexities of ion channel function.