KCNQ2/3/4/5 Polyclonal Antibody

The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.

The KCNQ2/3/4/5 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of KCNQ2, KCNQ3, KCNQ4, and KCNQ5 proteins. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target proteins.

The KCNQ2/3/4/5 Polyclonal Antibody is suitable for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated in multiple experimental settings, demonstrating excellent performance and consistent results.

This antibody exhibits exceptional sensitivity, allowing for the detection of low abundance KCNQ2, KCNQ3, KCNQ4, and KCNQ5 proteins in complex biological samples. Its high specificity ensures minimal cross-reactivity with other proteins, enabling accurate and reliable data interpretation.

The KCNQ2/3/4/5 Polyclonal Antibody is manufactured under strict quality control standards, ensuring batch-to-batch consistency and reproducibility. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation.

With its superior performance and reliability, the KCNQ2/3/4/5 Polyclonal Antibody is an indispensable tool for researchers studying the function and regulation of KCNQ2, KCNQ3, KCNQ4, and KCNQ5 proteins. Its versatility and robustness make it an ideal choice for a wide range of research applications in the field of neuroscience and beyond.