JMY Polyclonal Antibody

JMY is a Protein Coding gene. Junction-mediating and -regulatory protein acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics. May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments. The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location. Among its related pathways are Gene Expression and Direct p53 effectors. Gene Ontology (GO) annotations related to this gene include actin binding and transcription coactivator activity. An important paralog of this gene is WHAMM.

The JMY Polyclonal Antibody is a highly specific and sensitive antibody that has been designed to detect and quantify the JMY protein in various biological samples. This antibody has been extensively validated for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The JMY Polyclonal Antibody has been produced using state-of-the-art techniques and is of the highest quality. It has been purified using a combination of protein A and protein G chromatography to ensure maximum purity and specificity. The antibody has also been extensively tested to ensure that it does not cross-react with other proteins, ensuring that the results obtained are accurate and reliable.

The JMY Polyclonal Antibody is supplied in a convenient format, with a range of sizes available to suit your specific needs. It is also supplied with detailed instructions for use, ensuring that you can achieve the best possible results with minimal effort.

Overall, the JMY Polyclonal Antibody is an essential tool for researchers studying the JMY protein and its role in various biological processes. Its high specificity and sensitivity make it an ideal choice for a wide range of applications, and its quality and reliability ensure that you can trust the results obtained.