JMJD2B Polyclonal Antibody

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

The JMJD2B Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of JMJD2B protein expression in various biological samples. This antibody has been extensively validated for its exceptional sensitivity and specificity, ensuring accurate and reproducible results.

JMJD2B, also known as Jumonji domain-containing protein 2B, is a histone demethylase that plays a crucial role in the regulation of gene expression and chromatin remodeling. It is involved in various biological processes, including cell proliferation, differentiation, and development. Dysregulation of JMJD2B has been implicated in several diseases, including cancer and neurological disorders.

The JMJD2B Polyclonal Antibody has been developed using high-quality immunogens and advanced immunization techniques. It exhibits a high affinity and selectivity towards JMJD2B, enabling precise detection and quantification of the protein in complex biological samples. This antibody has been rigorously tested and validated in various experimental conditions, including Western blotting, immunohistochemistry, and immunofluorescence.

Key features of the JMJD2B Polyclonal Antibody include its excellent sensitivity, specificity, and reproducibility. It offers a wide range of applications, making it suitable for diverse research areas, such as cancer biology, epigenetics, and developmental biology. The antibody is supplied in a convenient format, ensuring ease of use and storage.

In summary, the JMJD2B Polyclonal Antibody is a reliable and versatile tool for the detection and analysis of JMJD2B protein expression. Its exceptional sensitivity and specificity make it an ideal choice for researchers seeking accurate and reproducible results in their studies.