JAM-A Polyclonal Antibody

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. F11 receptor encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

The JAM-A Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in various research applications. This antibody is produced using a polyclonal approach, which ensures that it recognizes multiple epitopes on the target protein, JAM-A. The JAM-A Polyclonal Antibody has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence assays.

This antibody is designed to detect JAM-A, a transmembrane protein that plays a crucial role in the regulation of cell adhesion and migration. JAM-A is expressed in a variety of tissues, including endothelial cells, leukocytes, and epithelial cells. The JAM-A Polyclonal Antibody has been shown to be highly specific for JAM-A and does not cross-react with other proteins.

The JAM-A Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum. This antibody is provided in a liquid format and is ready to use for various applications. The JAM-A Polyclonal Antibody has been optimized for use in a variety of experimental conditions and has been shown to provide consistent and reliable results.

In summary, the JAM-A Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in various research applications. This antibody is designed to detect JAM-A, a transmembrane protein that plays a crucial role in the regulation of cell adhesion and migration. The JAM-A Polyclonal Antibody has been extensively validated and optimized for use in Western blotting, immunohistochemistry, and immunofluorescence assays.