IKappaB- Alpha Polyclonal Antibody

NFKBIA encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

The IKappaB-Epsilon Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for the detection of IKappaB-Epsilon protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human IKappaB-Epsilon protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The IKappaB-Epsilon Polyclonal Antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been validated for use in human, mouse, and rat samples and has been shown to exhibit high specificity and sensitivity in detecting IKappaB-Epsilon protein.

This antibody is an essential tool for researchers studying the NF-kappaB signaling pathway, as IKappaB-Epsilon is a critical regulator of this pathway. It is also useful for investigating the role of IKappaB-Epsilon in various cellular processes, including inflammation, immune response, and cell survival.

In summary, the IKappaB-Epsilon Polyclonal Antibody is a high-quality, reliable, and specific antibody that is essential for researchers studying the NF-kappaB signaling pathway and investigating the role of IKappaB-Epsilon in various cellular processes.