Integrin  AlphaV Polyclonal Antibody

Integrin alpha-V encoded by ITGAV belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

The Integrin AlphaV Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Integrin AlphaV protein expression. This antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

Integrin AlphaV is a transmembrane glycoprotein that plays a crucial role in cell adhesion and migration. It is involved in various physiological and pathological processes, such as embryogenesis, angiogenesis, wound healing, and tumor metastasis. The Integrin AlphaV Polyclonal Antibody recognizes the extracellular domain of Integrin AlphaV and has been shown to exhibit minimal cross-reactivity with other integrin family members.

This antibody is produced using high-quality immunogens and undergoes rigorous quality control to ensure batch-to-batch consistency and optimal performance. It exhibits high sensitivity and specificity, enabling accurate and reliable detection of Integrin AlphaV expression in various sample types.

The Integrin AlphaV Polyclonal Antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is provided in a ready-to-use format, eliminating the need for additional reagents or preparation steps. This antibody is compatible with a wide range of experimental conditions and can be used in both research and clinical settings.

In summary, the Integrin AlphaV Polyclonal Antibody is a valuable tool for researchers and clinicians studying Integrin AlphaV protein expression. Its high specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications.