Integrin  Alpha4 Polyclonal Antibody

ITGA4 encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.

The Integrin Alpha4 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Integrin Alpha4 protein expression in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.

Integrin Alpha4 is a cell surface glycoprotein that plays a crucial role in cell adhesion and migration processes. It is involved in various physiological and pathological processes, including immune response, inflammation, and cancer metastasis. The Integrin Alpha4 Polyclonal Antibody recognizes the extracellular domain of Integrin Alpha4 and can be used for both immunohistochemistry and western blotting applications.

This antibody exhibits excellent specificity, showing minimal cross-reactivity with other integrin family members. It has been extensively validated in various cell lines and tissue samples, demonstrating reliable and reproducible results. The high sensitivity of this antibody allows for the detection of low levels of Integrin Alpha4 expression, making it an ideal tool for both basic research and clinical applications.

The Integrin Alpha4 Polyclonal Antibody is supplied as a liquid formulation, ready to use for immunostaining and western blotting experiments. It is provided in a convenient size, ensuring cost-effectiveness and minimizing waste. The antibody is stable for long-term storage at -20°C, allowing for multiple uses without compromising its performance.

In summary, the Integrin Alpha4 Polyclonal Antibody is a reliable and versatile tool for the detection and analysis of Integrin Alpha4 protein expression. Its high specificity, sensitivity, and stability make it an essential reagent for researchers and clinicians working in the fields of immunology, cancer biology, and inflammation.