Insulin R Polyclonal Antibody

INSR encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

The Insulin R Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of insulin receptor (IR) protein in various biological samples. This antibody is produced using a polyclonal approach, ensuring a diverse range of epitope recognition and enhanced sensitivity. With its exceptional affinity and specificity, this antibody enables accurate and reliable measurement of insulin receptor levels in both research and clinical settings.

The Insulin R Polyclonal Antibody is meticulously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring precise and specific detection of insulin receptor. This antibody is suitable for use in a wide range of species, including human, mouse, and rat, making it a versatile tool for diverse experimental designs.

This antibody is manufactured using high-quality materials and rigorous quality control measures to ensure consistent and reliable results. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. The Insulin R Polyclonal Antibody is provided in a convenient format, allowing for easy storage and long-term stability.

In summary, the Insulin R Polyclonal Antibody is a valuable tool for researchers and clinicians involved in the study of insulin receptor biology. Its exceptional sensitivity, specificity, and versatility make it an indispensable asset for various applications, enabling accurate and reliable measurement of insulin receptor levels in diverse biological samples.