IL-4R Alpha Polyclonal Antibody

IL4R encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. Interleukin-4 receptor subunit alpha also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.

The IL-4R Alpha Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of IL-4R Alpha protein expression. This antibody is produced using a polyclonal approach, ensuring a diverse range of antibodies that target different epitopes of the IL-4R Alpha protein.

The IL-4R Alpha Polyclonal Antibody exhibits exceptional affinity and selectivity towards IL-4R Alpha, making it an ideal choice for various applications, including Western blotting, immunohistochemistry, and flow cytometry. Its superior sensitivity allows for the detection of even low levels of IL-4R Alpha expression, enabling accurate and reliable results.

This antibody has been rigorously tested and validated to ensure its high quality and performance. It exhibits minimal cross-reactivity with other proteins, ensuring specific and reliable detection of IL-4R Alpha. Additionally, it demonstrates excellent reproducibility, providing consistent results across multiple experiments.

The IL-4R Alpha Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into laboratory workflows. It is provided in a liquid formulation, eliminating the need for reconstitution and minimizing the risk of sample contamination. Furthermore, it is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

In summary, the IL-4R Alpha Polyclonal Antibody is a highly reliable and efficient tool for the detection and quantification of IL-4R Alpha protein expression. Its exceptional sensitivity, specificity, and ease of use make it an invaluable asset for researchers in the fields of immunology, molecular biology, and biomedical research.