IL-4 Polyclonal Antibody

The protein encoded by IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

The IL-4 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Interleukin-4 (IL-4) in various biological samples. IL-4 is a cytokine that plays a crucial role in immune responses, particularly in the regulation of allergic and inflammatory reactions. This antibody is produced by immunizing animals with a synthetic peptide corresponding to a specific region of IL-4, ensuring its high affinity and specificity.

The IL-4 Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). It exhibits excellent sensitivity and specificity, allowing for accurate and reliable detection of IL-4 in complex biological matrices.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing waste. The IL-4 Polyclonal Antibody is compatible with a wide range of sample types, including cell lysates, tissue homogenates, and serum, making it suitable for diverse research applications.

With its exceptional performance and reliability, the IL-4 Polyclonal Antibody is an indispensable tool for researchers studying the role of IL-4 in various physiological and pathological processes. Its high specificity and sensitivity enable precise and reproducible quantification of IL-4, facilitating a deeper understanding of its functions and potential therapeutic applications.

For optimal results, it is recommended to follow the provided protocols and guidelines for sample preparation, antibody dilution, and detection methods. The IL-4 Polyclonal Antibody is backed by our dedicated technical support team, ensuring prompt assistance and troubleshooting for any inquiries or concerns.

In summary, the IL-4 Polyclonal Antibody is a superior research tool that offers exceptional sensitivity, specificity, and reliability for the detection and quantification of IL-4. Its versatility and compatibility with various applications make it an invaluable asset for researchers in the fields of immunology, allergy, inflammation, and beyond.